siRNA/miRNA transfection reagent

siRNA/miRNA Transfection Reagent delivers efficient RNA interference with low cytotoxicity via unique proton sponge mechanism in mammalian cells.

siRNA/miRNA Transfection Reagent by ImmunoClone is a non-liposomal cationic transfection reagent specifically designed for the efficient delivery of siRNA/miRNA into mammalian cells. It works by encapsulating nucleic acids to form positively charged complexes, which bind to negatively charged proteoglycans on the cell surface and are subsequently internalized via endocytosis. The reagent's unique proton sponge effect facilitates endosomal rupture, ensuring efficient release of siRNA/miRNA into the cytoplasm. This product is suitable for a wide range of cell types, delivering highly effective gene silencing in various adherent cell lines, suspension cell lines, and certain primary cells such as human fibroblasts.

siRNA/miRNA Transfection Reagent by ImmunoClone is specifically designed for the highly efficient delivery of siRNA/miRNA. Through careful design and rigorous screening, it minimizes damage to cells, maintains their normal physiological functions, viability, and intracellular environmental stability, thereby providing strong assurance for the accuracy and reliability of experimental results. The reagent achieves ultra-high transfection efficiency with extremely low cytotoxicity and offers broad applicability, including various adherent cells, difficult-to-transfect suspension cells, and primary cells. It serves as a reliable tool for siRNA/miRNA functional research.