HighQC™ Human Breast Cancer Stem Cells (BCSCs) are isolated from primary human breast carcinoma tissue and enriched for tumor-initiating potential using surface markers CD133, CD44, SSEA3/4, Oct4. These cells display an epithelial morphology with high clonogenicity and self-renewal ability, and they form mammospheres in suspension culture. BCSCs are known for their roles in metastasis, drug resistance, and tumor recurrence. HighQC™ Breast Cancer Stem Cells offer a robust in vitro model for studying tumor heterogeneity, breast cancer pathogenesis, and therapeutic resistance mechanisms. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.
HighQC™ Human Breast Cancer Stem Cell, Human Breast CSC, hBCSC, Human Mammary Cancer Progenitors
HighQC™ Human Breast Cancer Stem Cells, Human breast cancer stem cells (BCSCs), serve as a powerful tool for exploring cancer progression, metastasis, drug resistance, and recurrence. Their use is critical in developing targeted therapies, especially those designed to eliminate BCSCs and prevent relapse. These cells, as Breast tumor-initiating cells and Human mammary carcinoma CSCs, are widely used in 3D culture models, xenografts, EMT assays, and high-throughput drug screening to study molecular mechanisms of tumor initiation and therapeutic evasion. They are especially valuable in understanding hormone receptor signaling, HER2 pathways, and triple-negative breast cancer models, enabling precision oncology efforts.
Additional Information
Growth Mode
Adherent
Shipping Info
Dry Ice
Biosafety Level
1
Disease Model
Breast Cancer
Synonyms
HighQC™ Human Breast Cancer Stem Cell, Human Breast CSC, hBCSC, Human Mammary Cancer Progenitors
HighQC™ Human Brain Cancer Stem Cells are isolated from primary human glioblastoma tissues and enriched for tumor-initiating cells using markers such as CD133, CD44, CD34, SSEA 3/4, Oct4, confirmed by flow cytometry. These cells exhibit characteristic stem-like morphology with small, round shapes and the ability to form neurospheres in vitro. They possess self-renewal and multipotent differentiation capabilities, giving rise to heterogeneous tumor cell populations including neurons, astrocytes, and oligodendrocyte-like cells. These brain cancer stem cells (BCSCs) are critical for studying glioma initiation, progression, therapeutic resistance, and recurrence. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.
HighQC™ Human Gall Bladder Derived Cancer Stem Cells (HGBCSCs) are isolated from patient-derived gallbladder carcinoma tissues. These cells express characteristic cancer stem cell markers including CD133, CD44, SSEA3/4, Oct4, confirmed via FACS analysis. They form spheroids under serum-free, low-attachment conditions and exhibit enhanced resistance to chemotherapeutic agents. GBCSCs demonstrate self-renewal, multipotency, and the capacity to regenerate heterogeneous tumor populations in vivo. These cells can differentiate into both epithelial and mesenchymal phenotypes, making them valuable for tumor progression and metastasis studies. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.
