HighQC™ Human Brain Cancer Stem Cells are isolated from primary human glioblastoma tissues and enriched for tumor-initiating cells using markers such as CD133, CD44, CD34, SSEA 3/4, Oct4, confirmed by flow cytometry. These cells exhibit characteristic stem-like morphology with small, round shapes and the ability to form neurospheres in vitro. They possess self-renewal and multipotent differentiation capabilities, giving rise to heterogeneous tumor cell populations including neurons, astrocytes, and oligodendrocyte-like cells. These brain cancer stem cells (BCSCs) are critical for studying glioma initiation, progression, therapeutic resistance, and recurrence. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.
HighQC™ Human Brain Cancer Stem Cell, Human Brain CSC, hBCSC-Brain, Human Brain Cancer Progenitors
HighQC™ Human Brain Cancer Stem Cells are extensively used to model glioblastoma biology, including tumor growth, invasion, and resistance to chemotherapy and radiotherapy. These cells provide a robust platform for screening novel anti-cancer agents targeting cancer stem cell populations. They are also utilized in studies on tumor microenvironment interactions, signaling pathways, and mechanisms driving tumor recurrence. Their capacity to differentiate into various neural lineages makes them valuable for investigating glioma heterogeneity and developing precision medicine approaches in neuro-oncology.
Additional Information
Growth Mode
Adherent
Shipping Info
Dry Ice
Biosafety Level
1
Disease Model
Normal
Synonyms
HighQC™ Human Brain Cancer Stem Cell, Human Brain CSC, hBCSC-Brain, Human Brain Cancer Progenitors
HighQC™ Human Breast Cancer Stem Cells (BCSCs) are isolated from primary human breast carcinoma tissue and enriched for tumor-initiating potential using surface markers CD133, CD44, SSEA3/4, Oct4. These cells display an epithelial morphology with high clonogenicity and self-renewal ability, and they form mammospheres in suspension culture. BCSCs are known for their roles in metastasis, drug resistance, and tumor recurrence. HighQC™ Breast Cancer Stem Cells offer a robust in vitro model for studying tumor heterogeneity, breast cancer pathogenesis, and therapeutic resistance mechanisms. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.
HighQC™ Human Gall Bladder Derived Cancer Stem Cells (HGBCSCs) are isolated from patient-derived gallbladder carcinoma tissues. These cells express characteristic cancer stem cell markers including CD133, CD44, SSEA3/4, Oct4, confirmed via FACS analysis. They form spheroids under serum-free, low-attachment conditions and exhibit enhanced resistance to chemotherapeutic agents. GBCSCs demonstrate self-renewal, multipotency, and the capacity to regenerate heterogeneous tumor populations in vivo. These cells can differentiate into both epithelial and mesenchymal phenotypes, making them valuable for tumor progression and metastasis studies. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.
