The JC-1 Mitochondrial Membrane Potential Assay Kit uses JC-1 as a rapid and sensitive detection fluorescent probe for changes in mitochondrial membrane.
The JC-1 Mitochondrial Membrane Potential Assay Kit uses JC-1 as a fluorescent probe for rapid and sensitive detection of changes in mitochondrial membrane potential (ΔΨm) in cells, tissues, or purified samples. It is widely applied for the early detection of apoptosis, as mitochondrial membrane depolarization is a key early apoptotic event.
JC-1 accumulates in mitochondria in a membrane potential–dependent manner. In healthy mitochondria with intact ΔΨm, JC-1 forms aggregates within the mitochondrial matrix, emitting strong red fluorescence (Ex = 585 nm, Em = 590 nm). When mitochondrial membrane potential decreases or collapses, JC-1 remains in its monomeric form in the cytoplasm and emits green fluorescence (Ex = 514 nm, Em = 529 nm). The shift from red to green fluorescence allows both qualitative visualization and quantitative analysis of mitochondrial depolarization by calculating the red-to-green fluorescence intensity ratio.
| 产品名称 | JC-1 Mitochondrial Membrane Potential Assay Kit |
|---|---|
| 中文名称 | 请咨询 |
| Cat No. 目录编号 | ABC-BR0063 |
| Product Type 产品类型 | Cell Biology Reagents（细胞生物学试剂） |
| 规格 | 100 T |
| 储存条件 | -20℃, protect from light, avoid repeated freezing and thawing. |
| 价格 | 价格请询价 |
| 文档名称 | 类型 | 语言 | 说明 |
|---|---|---|---|
| 产品说明书（Product Manual） | 中 / 英 | 含复溶、稀释、储存与使用操作说明 | |
| 质检报告（COA） | 英 | 按批次出具，随货提供 | |
| 安全数据表（MSDS） | 中 / 英 | 危险组分识别、防护措施与应急处置 |
