Human BCR_ABL (F317V) BAF3 Cell Line
The BCR-ABL (F317V) BAF3 Cell Line is designed for modeling ABL kinase inhibitor resistance and screening next-generation anti-leukemia agents.
敲除 / 敲低 / 敲入 / 过表达稳转细胞系与敲除细胞裂解物,按「基因 × 细胞系」粒度提供,支持定制建株。 共 1,221 个产品。
The BCR-ABL (F317V) BAF3 Cell Line is designed for modeling ABL kinase inhibitor resistance and screening next-generation anti-leukemia agents.
Human BCR_ABL (F359I) BAF3 Cell Line is designed to explore functional consequences of BCR-ABL mutations in leukemia progression and therapy.
The human BCR_ABL (F359L) BAF3 Cell Line supports research on tyrosine kinase inhibitor resistance mechanisms in hematological malignancies.
Human BCR_ABL (H396P) BAF3 Cell Line facilitates comprehensive drug resistance and mutation impact studies in chronic myeloid leukemia models.
Human BCR_ABL (M244V) BAF3 Cell Line, BCR, ABL, Overexpression Stable Cell Lines, Transfected Stable Cell Lines
The human BCR-ABL (M244V) BAF3 Cell Line models tyrosine kinase mutations to support research on leukemia progression and therapeutic resistance.
The human BCR_ABL (M351T) BAF3 Cell Line serves as an effective model to study therapeutic resistance in BCR-ABL positive leukemia research.
Human BCR_ABL (P465S) BAF3 Cell Line serves as a model to assess resistance mutations in BCR-ABL-driven leukemia and potential therapeutic strategies.
Human BCR_ABL (V299L) BAF3 Cell Line aids in analyzing mutation-induced resistance to targeted leukemia treatments in vitro experimental models.
Human BCR_ABL (V468F) BAF3 Cell Line facilitates exploration of BCR-ABL-mediated drug resistance mechanisms and targeted therapy development.
The human BCR_ABL (Y253H) BAF3 Cell Line enables investigation of mutation-driven treatment resistance in chronic myeloid leukemia research.
Human BCR-ABL (E355G) BAF3 Cell Line supports analysis of tyrosine kinase inhibitor resistance caused by BCR-ABL point mutations in leukemic cells.
Human BEX3 knockout cell line provides a genetic model for neuronal development, apoptosis regulation, and functional cellular pathway studies.
Human BRAF (G464R) BAF3 Cell Line enables exploration of BRAF mutation-induced MAPK pathway activation and its implications for drug development.
Human BRAF (G464V) BAF3 Cell Line enables detailed research on BRAF mutations involved in MAPK pathway dysregulation and therapy resistance.
The human BRAF (G466A) BAF3 cell line is designed for studying non-classical BRAF mutations and their roles in tumors, supporting drug development.
The human BRAF (G469A) NIH/3T3 cell line provides a reliable platform for tumor research, supporting high-throughput screening and BRAF-dependent studies.
The BRAF (K601N) BAF3 cell line is an important tool for studying BRAF-driven tumors, supporting in-depth exploration of drug resistance mechanisms.
Human BRAF (L597Q) BAF3 Cell Line facilitates research on BRAF mutations involved in MAPK pathway activation and targeted cancer therapies.
The BRAF (L597Q) NIH/3T3 cell line is a powerful tool for investigating tumor mechanisms, supporting targeted drug screening and resistance analysis.
Human BRAF (L597R) BAF3 Cell Line supports detailed investigation of BRAF mutation-driven oncogenic signaling and drug response in cancer models.
BRCA1 Knockout Cell Line is a genetically engineered model derived from different host cell lines based on customers’ requirement. Among various options, HEK293, a human embryonic kidney cell line, is one of the most commonly selected parental cell line. BRCA1 knockout line is usually generated via CRISPR/Cas9-mediated gene editing. The edited cells are maintained at low passage numbers ( P20). Knockout clone is validated either at gene level or protein level by PCR, Sanger Sequencing or Western Blot. Target The BRCA1 gene encodes a tumor suppressor protein that plays a central role in DNA damage repair, cell cycle checkpoint control, and genome stability. BRCA1 loss is associated with increased risk of breast, ovarian, and other cancers due to impaired homologous recombination repair and genomic instability.
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Human BRCA2 knockout cell line enables studies on DNA repair mechanisms, cancer biology, and breast/ovarian cancer susceptibility through gene knockout.
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