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Induced Pluripotent Stem Cells (iPSCs)

诱导多能干细胞

本分类收录的细胞产品与配套技术资料,支持按来源、物种与规格筛选。 共 293 个产品。

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诱导多能干细胞

HighQC™ Human Induced Pluripotent Stem Cells, From Amyotrophic Lateral Sclerosis

HighQC™ human induced pluripotent stem cells derived from skin fibroblasts of patients with amyotrophic lateral sclerosis (ALS). These cells exhibit a high nuclear-to-cytoplasmic ratio with prominent nucleoli and grow as compact colonies under feeder-free, adherent conditions. These cells are generated by transducing OCT4, SOX2, KLF4, and c-MYC into patient-derived skin fibroblasts using Sendai virus. They express pluripotency markers including OCT4, SSEA4. These cells exhibit self-renewal capacity and retain the full pluripotent differentiation potential into all three germ layers—ectoderm, mesoderm, and endoderm under directed differentiation protocols. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0211Human1 vial
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诱导多能干细胞

HighQC™ Human Induced Pluripotent Stem Cells, From Friedreich Ataxia 1

HighQC™ Human Induced Pluripotent Stem Cells, From Friedreich Ataxia 1 are derived from patients with Friedreich Ataxia (FRDA). These cells are generated using a retroviral vector to deliver the transcription factors OCT4, SOX2, KLF4, and c-MYC. Donor cells are clinically affected by ataxia, cardiomyopathy, and mild peripheral neuropathy, and are homozygous for the GAA trinucleotide repeat expansion in the FXN gene in the frataxin gene with alleles of approximately 541 and 420 repeats. These cells was evaluated for viability surface antigen expression and alkaline phosphatase activity. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0230Human1 vial
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诱导多能干细胞

HighQC™ Human Induced Pluripotent Stem Cells, From Healthy Adult

HighQC™ Human Induced Pluripotent Stem Cells, From Healthy Adult, derived from healthy adult donors, are generated using an RNA-based Sendai virus to deliver reprogramming factors to donor skin fibroblasts. Since the virus does not go through a DNA phase, its genetic material and transgenes do not integrate into the host cell genome. These cells express key pluripotency markers OCT4, Nanog, LIN28 and SSEA-4. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0243Human1 vial
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诱导多能干细胞

HighQC™ Human Induced Pluripotent Stem Cells, From Muscular dystrophy

HighQC™ Human Induced Pluripotent Stem Cells, From Muscular Dystrophy, are derived from patients with Muscular Dystrophy and reprogrammed using a non-integrating episomal vector system. Reprogramming is achieved through transient expression of a defined combination of transcription factors, typically including OCT4, SOX2, KLF4, and c-MYC. These cells retain robust differentiation potential, capable of generating cell lineages representative of the three germ layers—ectoderm, mesoderm, and endoderm—through directed differentiation protocols. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0233Human1 vial
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诱导多能干细胞

HighQC™ Human Induced Pluripotent Stem Cells, From Parkinson Disease

HighQC™ human induced pluripotent stem cells derived from fibroblasts of Parkinson's disease patients are generated using an RNA-based Sendai virus. These cells express pluripotency markers such as OCT4 and SSEA4. Cytogenetic analysis demonstrates a normal human karyotype and long-term genetic stability across multiple passages. These cells retain full differentiation capacity, enabling their directed differentiation into all three germ layers—ectoderm, mesoderm, and endoderm—under appropriate conditions. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0189Human1 vial
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诱导多能干细胞

HighQC™ Human Induced Pluripotent Stem Cells, From Rett Syndrome

HighQC™ Human Induced Pluripotent Stem Cells, From Rett Syndrome, are generated using a non-integrating Sendai virus vector system to deliver a defined set of reprogramming transcription factors, typically including OCT4, SOX2, KLF4, and c-MYC. These cells display typical pluripotent stem cell characteristics, including a high nucleus-to-cytoplasm ratio and prominent nucleoli. The donor carries a frameshift mutation (1155del32) in the MECP2 gene, characteristic of Rett Syndrome. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0235Human1 vial
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诱导多能干细胞

HighQC™ Human Induced Pluripotent Stem Cells, From Schizophrenia

HighQC™ Human Induced Pluripotent Stem Cells, From Schizophrenia, are derived from patients diagnosed with schizophrenia. These cells are generated using lentiviral vectors to deliver reprogramming factors to fibroblasts and are cultured under a feeder layer. These cells are generated by transducing four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc, into skin fibroblasts using non-integrating methods. They express key pluripotency markers such as OCT4 and SSEA-4. These cells retain the full differentiation potential to generate all three germ layers — ectoderm, mesoderm, and endoderm — enabling the development of relevant neural cell types, including cortical neurons and glial cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0231Human1 vial
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诱导多能干细胞

HighQC™ Human Induced Pluripotent Stem Cells, From Spinal Muscular Atrophy I

HighQC™ Human Induced Pluripotent Stem Cells, From Spinal Muscular Atrophy, are derived from patients with Spinal Muscular Atrophy Type II (SMA) and generated by reprogramming somatic cells using integrating lentiviral vectors encoding a defined set of pluripotency-associated transcription factors, including OCT4, SOX2, NANOG, and LIN28. These iPSCs exhibit characteristic pluripotent stem cell morphology, such as a high nucleus-to-cytoplasm ratio and prominent nucleoli. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0238Human1 vial
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诱导多能干细胞

HighQC™ Human Induced Pluripotent Stem Cells, From Tay-sachs

HighQC™ human induced pluripotent stem cells (iPSCs) from Tay-Sachs disease patients are derived from patient fibroblasts carrying disease-specific HEXA mutations. These cells exhibit classical pluripotent stem cell morphology. They are generated by transducing four transcription factors OCT4, SOX2, KLF4, and c-MYC into patient fibroblasts using Sendai virus. The expanded line was evaluated for viability surface antigen expression and alkaline phosphatase activity. Pluripotency was assessed via embryoid body (EB) formation. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0229Human1 vial
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诱导多能干细胞

HighQC™ Human IPS Cell (IPSC From Adipose/ Parkinson/ Episomal)

HighQC™ Human iPSCs (iPSC From Adipose/ Parkinson/ Episomal) are integration-free induced pluripotent stem cells derived from adipose tissue fibroblasts through episomal reprogramming. Reprogramming is achieved through episomal delivery of defined transcription factors, including OCT4, SOX2, KLF4, c-MYC, and LIN28. These cells express pluripotency markers including OCT4, NANOG, SSEA-4, and TRA-1-60, and can efficiently differentiate into functionally active dopaminergic neurons, a key neuronal subtype affected in Parkinson's disease. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0007THuman1 vial
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诱导多能干细胞

HighQC™ Human IPS Cell (IPSC From Fibroblast/ Diabetes Type II/ Episomal)

HighQC™ Human iPSCs (iPSC From Fibroblast/ Diabetes Type II/ Episomal) are a type of disease-specific induced pluripotent stem cell line derived from dermal fibroblasts of a Type 2 Diabetes Mellitus (T2D) donor. Reprogramming was achieved via episomal delivery. These cells exhibit high expression of pluripotency markers such as SOX2, TRA-1-60, OCT4, and SSEA-4, and display typical colony morphology with high nucleus-to-cytoplasm ratios. They retain the capacity to differentiate into cells of all three germ layers, including insulin-producing pancreatic β-cells. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0010THuman1 vial
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诱导多能干细胞

HighQC™ Human IPS Cell (IPSC From Fibroblast/ Parkinson/ Episomal)

HighQC™ Human iPSCs (iPSCs From Fibroblasts / Parkinson’s Disease / Episomal) are induced pluripotent stem cells derived from dermal fibroblasts. The cells express canonical stem cell markers including TRA-1-60, SOX2, OCT4, NANOG, and SSEA-4, confirming the maintenance of a stable undifferentiated state. They display robust trilineage differentiation capacity and can be directed toward midbrain dopaminergic neurons and glial subtypes, making them a valuable human model for Parkinson's disease. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

ABC-SC0006THuman1 vial
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诱导多能干细胞

HighQC™ Human iPSC Derived AFE Progenitors

Human iPSC Derived AFE Progenitors provide high-quality, defined cells for endodermal lineage differentiation, regenerative therapy, and disease modeling.

ABC-SC019YHuman1 vial
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诱导多能干细胞

HighQC™ Human iPSC Derived Pericytes

HighQC™ Human iPSC Derived Pericytes,iPSC-derived pericytes for vascular biology, blood-brain barrier studies,tissue engineering and regenerative research.

ABC-SC020YHuman1 vial
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诱导多能干细胞

HighQC™ Human IPSC From B-Lymphocyte-Apparently Healthy Individual

HighQC™ Human IPSC From B-Lymphocyte-Apparently Healthy Individual is a human induced pluripotent stem cell line generated from B-lymphocytes isolated from the peripheral blood mononuclear cells (PBMCs) of a healthy donor. The cells serve as ideal controls for stem cell and developmental mechanism studies. The resulting iPSCs (induced pluripotent stem cells) exhibit adherent growth with a high nucleus-to-cytoplasm ratio. They retain the fundamental capacity for trilineage differentiation into cell types of the ectoderm, mesoderm, and endoderm germ layers. These cells express the core pluripotency marker SSEA-4. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

ABC-SC2069Human1 vial
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