Recombinant Human Laminin 511 E8 Protein

Laminin is a trimeric basement membrane protein with α, β, γ chains, supporting cell adhesion, stem cell self-renewal, pluripotency, and differentiation.

Laminin is a cruciform trimeric protein composed of α, β, and γ chains. It is a major component of basement membranes and is widely distributed throughout the basement membranes of various tissues in the early embryo and adult life. Laminin possesses multiple cell-binding motifs that bind to cellular integrins and proteoglycans, activating signaling pathways that regulate the self-renewal and pluripotency of pluripotent stem cells. Laminin 521 and laminin 511 are two important isoforms, with potential to maintain the proliferation and specialized differentiation of pluripotent stem cells.

Aliquot the protein solution according to the single-use dose and store at -20 °C, avoiding repeated freeze-thaw cycles.