Hepatocyte growth factor is a potent mitogen for mature parenchymal hepatocyte cells, acts as a growth factor for a broad spectrum of tissues and cells.
Hepatocyte growth factor (HGF) contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. Structurally related to the peptidase S1 family, HGF itself has no detectable protease activity. The hepatocyte growth factor is secreted by mesenchymal cells as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor, and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility and matrix invasion gives it a central role in angiogenesis, tumorigenesis, and tissue regeneration.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
| 产品名称 | Human HGF Protein |
|---|---|
| 中文名称 | 请咨询 |
| Cat No. 目录编号 | ABC-GF0038 |
| Product Type 产品类型 | Growth Factors & Cytokines（生长因子与细胞因子） |
| Species 物种 | Human |
| 规格 | 20 µg/100 µg/500 µg |
| 运输条件 Shipping | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
| 储存条件 | -20°C |
| 价格 | 价格请询价 |
| 文档名称 | 类型 | 语言 | 说明 |
|---|---|---|---|
| 产品说明书（Product Manual） | 中 / 英 | 含复溶、稀释、储存与使用操作说明 | |
| 质检报告（COA） | 英 | 按批次出具，随货提供 | |
| 安全数据表（MSDS） | 中 / 英 | 危险组分识别、防护措施与应急处置 |
